Entinostat reverses P-glycoprotein activation in snail-overexpressing adenocarcinoma HCC827 cells

Epithelial-to-mesenchymal transition (EMT) in cancer cells facilitates tumor progression by promoting invasion and metastasis. Snail is a transcriptional factor that induces EMT, while P-glycoprotein (P-gp) is an efflux transporter involved in anticancer drug resistance, and P-gp efflux activity is...

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Detalles Bibliográficos
Autores principales: Tomono, Takumi, Machida, Tatsuya, Kamioka, Hiroki, Shibasaki, Yumi, Yano, Kentaro, Ogihara, Takuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034804/
https://www.ncbi.nlm.nih.gov/pubmed/29979729
http://dx.doi.org/10.1371/journal.pone.0200015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034804/
https://www.ncbi.nlm.nih.gov/pubmed/29979729
http://dx.doi.org/10.1371/journal.pone.0200015

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