Cargando…

Entinostat reverses P-glycoprotein activation in snail-overexpressing adenocarcinoma HCC827 cells

Epithelial-to-mesenchymal transition (EMT) in cancer cells facilitates tumor progression by promoting invasion and metastasis. Snail is a transcriptional factor that induces EMT, while P-glycoprotein (P-gp) is an efflux transporter involved in anticancer drug resistance, and P-gp efflux activity is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tomono, Takumi, Machida, Tatsuya, Kamioka, Hiroki, Shibasaki, Yumi, Yano, Kentaro, Ogihara, Takuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034804/ https://www.ncbi.nlm.nih.gov/pubmed/29979729 http://dx.doi.org/10.1371/journal.pone.0200015

Ejemplares similares

Physiological Roles of ERM Proteins and Transcriptional Regulators in Supporting Membrane Expression of Efflux Transporters as Factors of Drug Resistance in Cancer
por: Ogihara, Takuo, et al.
Publicado: (2020)

Gastrointestinal absorption of pimozide is enhanced by inhibition of P-glycoprotein
por: Morishita, Hiroki, et al.
Publicado: (2020)

Glycyrrhizin Suppresses the Growth of Human NSCLC Cell Line HCC827 by Downregulating HMGB1 Level
por: Wu, Xiaojin, et al.
Publicado: (2018)

Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function
por: Van Der Steen, Nele, et al.
Publicado: (2020)

Molecular mechanism of acquired drug resistance in the EGFR‐TKI resistant cell line HCC827‐TR
por: Yu, Tao, et al.
Publicado: (2020)

The Effect and Mechanism of Curcumin Combined with Carboplatin Chemotherapy Promoting on Apoptosis of Lung Cancer HCC827 Cells
por: Huang, Lingping, et al.
Publicado: (2022)

HIF-1 Inhibitor YC-1 Reverses the Acquired Resistance of EGFR-Mutant HCC827 Cell Line with MET Amplification to Gefitinib
por: Jin, Qian, et al.
Publicado: (2021)

AURKA upregulation plays a role in fibroblast-reduced gefitinib sensitivity in the NSCLC cell line HCC827
por: CHEN, JIA, et al.
Publicado: (2015)

The Effects of a Curcumin Derivative and Osimertinib on Fatty Acyl Metabolism and Mitochondrial Functions in HCC827 Cells and Tumors
por: Hsieh, Min-Tsang, et al.
Publicado: (2023)

IGF1R depletion facilitates MET-amplification as mechanism of acquired resistance to erlotinib in HCC827 NSCLC cells
por: Hussmann, Dianna, et al.
Publicado: (2017)

Icotinib-resistant HCC827 cells produce exosomes with mRNA MET oncogenes and mediate the migration and invasion of NSCLC
por: Yu, Yiming, et al.
Publicado: (2019)

Revisiting entinostat as an immune-potentiating adjuvant
por: McCaw, Tyler R., et al.
Publicado: (2018)

Preclinical rationale for entinostat in embryonal rhabdomyosarcoma
por: Bharathy, Narendra, et al.
Publicado: (2019)

GLP2-GLP2R signal affects the viability and EGFR-TKIs sensitivity of PC9 and HCC827 cells
por: Song, Bin, et al.
Publicado: (2022)

Claudin-7 modulates cell-matrix adhesion that controls cell migration, invasion and attachment of human HCC827 lung cancer cells
por: Kim, Do Hyung, et al.
Publicado: (2019)

MET amplification and epithelial-to-mesenchymal transition exist as parallel resistance mechanisms in erlotinib-resistant, EGFR-mutated, NSCLC HCC827 cells
por: Jakobsen, K R, et al.
Publicado: (2017)

M2 macrophages reduce the effect of gefitinib by activating AKT/mTOR in gefitinib‐resistant cell lines HCC827/GR
por: Xiao, Fengqi, et al.
Publicado: (2020)

下调HOTAIR通过提高PTEN表达逆转HCC827细胞吉非替尼耐药
Publicado: (2020)

Targeting SALL4 by entinostat in lung cancer
por: Yong, Kol Jia, et al.
Publicado: (2016)

Entinostat-Bortezomib Hybrids against Multiple Myeloma
por: Ferro, Angelica, et al.
Publicado: (2023)

Functional evaluation of therapeutic response of HCC827 lung cancer to bevacizumab and erlotinib targeted therapy using dynamic contrast-enhanced and diffusion-weighted MRI
por: Chen, Yi-Fang, et al.
Publicado: (2017)

吉非替尼对肺癌细胞株HCC827和H358放射敏感性的影响及其机制研究
Publicado: (2012)

Omega-3 Fatty Acid-Enriched Fish Oil and Selenium Combination Modulates Endoplasmic Reticulum Stress Response Elements and Reverses Acquired Gefitinib Resistance in HCC827 Lung Adenocarcinoma Cells
por: Liao, Chien-Huang, et al.
Publicado: (2020)

吉非替尼耐药的人肺腺癌HCC-827/GR细胞乙醛脱氢酶亚型表达分析
Publicado: (2018)

Phase I Trial of Regorafenib, Hydroxychloroquine, and Entinostat in Metastatic Colorectal Cancer
por: Karasic, Thomas B, et al.
Publicado: (2022)

LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling
por: Wang, Qiang, et al.
Publicado: (2020)

LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling [Corrigendum]
Publicado: (2021)

LHX6 Affects Erlotinib Resistance and Migration of EGFR-Mutant Non-Small-Cell Lung Cancer HCC827 Cells Through Suppressing Wnt/β-Catenin Signaling [Corrigendum]
Publicado: (2021)

Lamp2 inhibits epithelial-mesenchymal transition by suppressing Snail expression in HCC
por: Zheng, Hao, et al.
Publicado: (2018)

Histone deacetylase inhibition by Entinostat for the prevention of electrical and structural remodeling in heart failure
por: Freundt, Johanna K., et al.
Publicado: (2019)

The PEMDAC phase 2 study of pembrolizumab and entinostat in patients with metastatic uveal melanoma
por: Ny, Lars, et al.
Publicado: (2021)

Utility of Three-Dimensional Cultures of Primary Human Hepatocytes (Spheroids) as Pharmacokinetic Models
por: Mizoi, Kenta, et al.
Publicado: (2020)

Partitas No. 3, BWV 827 [A minor], No. 4 BWV 828 [D major]
por: Bach, Johann Sebastian, 1685-1750
Publicado: (1993)

circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation
por: Hollensen, Anne Kruse, et al.
Publicado: (2020)

Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC
por: Lin, Zhong-Zhe, et al.
Publicado: (2010)

NF-Y Overexpression in Liver Hepatocellular Carcinoma (HCC)
por: Bezzecchi, Eugenia, et al.
Publicado: (2020)

Combination of NK cells therapy and oral administration of entinostat as an approach for osteosarcoma lung metastasis treatment
por: Kiany, Simin, et al.
Publicado: (2015)

The histone deacetylase inhibiting drug Entinostat induces lipid accumulation in differentiated HepaRG cells
por: Nunn, Abigail D. G., et al.
Publicado: (2016)

MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells
por: Cassandri, Matteo, et al.
Publicado: (2021)

Genetic Regulation by NLA and MicroRNA827 for Maintaining Nitrate-Dependent Phosphate Homeostasis in Arabidopsis
por: Kant, Surya, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_thh3mitcuoc51t03js9hqhqdgg