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A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association study

A chronic inflammatory state to a large extent explains sickle cell disease (SCD) pathophysiology. Nonetheless, the principal dysregulated factors affecting this major pathway and their mechanisms of action still have to be fully identified and elucidated. Integrating gene expression and genome-wide...

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Detalles Bibliográficos
Autores principales: Ben Hamda, Cherif, Sangeda, Raphael, Mwita, Liberata, Meintjes, Ayton, Nkya, Siana, Panji, Sumir, Mulder, Nicola, Guizani-Tabbane, Lamia, Benkahla, Alia, Makani, Julie, Ghedira, Kais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034806/
https://www.ncbi.nlm.nih.gov/pubmed/29979707
http://dx.doi.org/10.1371/journal.pone.0199461