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A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association study
A chronic inflammatory state to a large extent explains sickle cell disease (SCD) pathophysiology. Nonetheless, the principal dysregulated factors affecting this major pathway and their mechanisms of action still have to be fully identified and elucidated. Integrating gene expression and genome-wide...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034806/ https://www.ncbi.nlm.nih.gov/pubmed/29979707 http://dx.doi.org/10.1371/journal.pone.0199461 |