Physcion 8-O-β-glucopyranoside extracted from Polygonum cuspidatum exhibits anti-proliferative and anti-inflammatory effects on MH7A rheumatoid arthritis-derived fibroblast-like synoviocytes through the TGF-β/MAPK pathway

The present study aimed to investigate the anti-arthritic effect of physcion 8-O-β-glucopyranoside (POGD) and its possible mechanisms. The anti-proliferative effects of POGD on MH7A cells were detected using a CCK-8 assay, and the release of pro-inflammatory cytokines, interleukin (IL)-1β, IL-6, IL-...

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Detalles Bibliográficos
Autores principales: Geng, Qin, Wei, Qiaofeng, Wang, Shujun, Qi, Huili, Zhu, Qin, Liu, Xia, Shi, Xiaojun, Wen, Shuyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034927/
https://www.ncbi.nlm.nih.gov/pubmed/29717774
http://dx.doi.org/10.3892/ijmm.2018.3649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034927/
https://www.ncbi.nlm.nih.gov/pubmed/29717774
http://dx.doi.org/10.3892/ijmm.2018.3649

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