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Upregulation of allograft inflammatory factor-1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype

Macrophages have been identified as a key cell type in the pathogenesis of renal interstitial fibrosis (RIF). However, the mechanism through which macrophages drive fibrosis remains unclear. The current study focuses on the effects and possible underlying mechanism of allograft inflammatory factor-1...

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Detalles Bibliográficos
Autores principales: Li, Yushu, Wang, Xingzhi, Zhang, Lei, Yuan, Xueying, Hao, Jianbing, Ni, Jie, Hao, Lirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034929/
https://www.ncbi.nlm.nih.gov/pubmed/29749461
http://dx.doi.org/10.3892/ijmm.2018.3667