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Upregulation of allograft inflammatory factor-1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype
Macrophages have been identified as a key cell type in the pathogenesis of renal interstitial fibrosis (RIF). However, the mechanism through which macrophages drive fibrosis remains unclear. The current study focuses on the effects and possible underlying mechanism of allograft inflammatory factor-1...
Autores principales: | Li, Yushu, Wang, Xingzhi, Zhang, Lei, Yuan, Xueying, Hao, Jianbing, Ni, Jie, Hao, Lirong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034929/ https://www.ncbi.nlm.nih.gov/pubmed/29749461 http://dx.doi.org/10.3892/ijmm.2018.3667 |
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