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Synergistic assembly of human pre-spliceosomes across introns and exons
Most human genes contain multiple introns, necessitating mechanisms to effectively define exons and ensure their proper connection by spliceosomes. Human spliceosome assembly involves both cross-intron and cross-exon interactions, but how these work together is unclear. We examined in human nuclear...
Autores principales: | Braun, Joerg E, Friedman, Larry J, Gelles, Jeff, Moore, Melissa J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035042/ https://www.ncbi.nlm.nih.gov/pubmed/29932423 http://dx.doi.org/10.7554/eLife.37751 |
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