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An Exploratory Study of Daprodustat in Erythropoietin-Hyporesponsive Subjects

INTRODUCTION: Hyporesponsiveness to recombinant human erythropoietin (rhEPO) is a major problem affecting some patients with chronic kidney disease (CKD), predominantly those on hemodialysis (HD). Daprodustat (GSK1278863) is a hypoxia-inducible factor prolyl hydroxylase inhibitor that is being inves...

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Detalles Bibliográficos
Autores principales: Cizman, Borut, Sykes, Andy P., Paul, Gitanjali, Zeig, Steven, Cobitz, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035126/
https://www.ncbi.nlm.nih.gov/pubmed/29989040
http://dx.doi.org/10.1016/j.ekir.2018.02.009