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Intestinal permeability, digestive stability and oral bioavailability of dietary small RNAs

Impactful dietary RNA delivery requires improving uptake and enhancing digestive stability. In mouse feeding regimes, we have demonstrated that a plant-based ribosomal RNA (rRNA), MIR2911, is more bioavailable than synthetic MIR2911 or canonical microRNAs (miRNAs). Here mutagenesis was used to disce...

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Detalles Bibliográficos
Autores principales: Yang, Jian, Elbaz-Younes, Ismail, Primo, Cecilia, Murungi, Danna, Hirschi, Kendal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035168/
https://www.ncbi.nlm.nih.gov/pubmed/29980707
http://dx.doi.org/10.1038/s41598-018-28207-1