Chemo-manipulation of tumor blood vessels by a metal-based anticancer complex enhances antitumor therapy

Human pleural mesothelioma is an incurable and chemoresistant cancer. Using a nude mouse xenograft model of human pleural mesothelioma, we show that RAPTA-T, a compound undergoing preclinical evaluation, enhances tumor vascular function by decreasing blood vessel tortuosity and dilation, while incre...

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Detalles Bibliográficos
Autores principales: Riedel, Tina, Cavin, Sabrina, van den Bergh, Hubert, Krueger, Thorsten, Liaudet, Lucas, Ris, Hans-Beat, Dyson, Paul J., Perentes, Jean Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035176/
https://www.ncbi.nlm.nih.gov/pubmed/29980753
http://dx.doi.org/10.1038/s41598-018-28589-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035176/
https://www.ncbi.nlm.nih.gov/pubmed/29980753
http://dx.doi.org/10.1038/s41598-018-28589-2

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