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Chemo-manipulation of tumor blood vessels by a metal-based anticancer complex enhances antitumor therapy
Human pleural mesothelioma is an incurable and chemoresistant cancer. Using a nude mouse xenograft model of human pleural mesothelioma, we show that RAPTA-T, a compound undergoing preclinical evaluation, enhances tumor vascular function by decreasing blood vessel tortuosity and dilation, while incre...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035176/ https://www.ncbi.nlm.nih.gov/pubmed/29980753 http://dx.doi.org/10.1038/s41598-018-28589-2 |