Interaction between parasite-encoded JAB1/CSN5 and macrophage migration inhibitory factor proteins attenuates its proinflammatory function

Multiple protozoans produce homologs of the cytokine MIF which play a role in immune evasion, invasion and pathogenesis. However, how parasite-encoded MIF activity is controlled remains poorly understood. Cytokine activity can be inhibited by intracellular binding partners that are released in the e...

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Detalles Bibliográficos
Autores principales: Ghosh, Swagata, Leaton, Laura Ann, Farr, Laura, Barfield, Alexis, Moonah, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035221/
https://www.ncbi.nlm.nih.gov/pubmed/29980718
http://dx.doi.org/10.1038/s41598-018-28625-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035221/
https://www.ncbi.nlm.nih.gov/pubmed/29980718
http://dx.doi.org/10.1038/s41598-018-28625-1

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