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Iron-Overload triggers ADAM-17 mediated inflammation in Severe Alcoholic Hepatitis

Severe alcoholic hepatitis (SAH) is associated with iron accumulation in hepatocytes/macrophages. This possibly correlates with inflammation and stress but the exact mechanism still remains obscure. To understand the role of iron and the mechanisms of systemic iron-overload, a transcriptomic study o...

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Detalles Bibliográficos
Autores principales: Maras, Jaswinder Singh, Das, Sukanta, Sharma, Sachin, Sukriti, Sukriti, kumar, Jitendra, Vyas, Ashish Kumar, Kumar, Dhananjay, Bhat, Adil, Yadav, Gaurav, Choudhary, Manish Chandra, Sharma, Shvetank, kumar, Guresh, Bihari, Chhagan, Trehanpati, Nirupma, Maiwall, Rakhi, Sarin, Shiv Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035223/
https://www.ncbi.nlm.nih.gov/pubmed/29980709
http://dx.doi.org/10.1038/s41598-018-28483-x