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Iron-Overload triggers ADAM-17 mediated inflammation in Severe Alcoholic Hepatitis
Severe alcoholic hepatitis (SAH) is associated with iron accumulation in hepatocytes/macrophages. This possibly correlates with inflammation and stress but the exact mechanism still remains obscure. To understand the role of iron and the mechanisms of systemic iron-overload, a transcriptomic study o...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035223/ https://www.ncbi.nlm.nih.gov/pubmed/29980709 http://dx.doi.org/10.1038/s41598-018-28483-x |