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Genetic deficiency of NOD2 confers resistance to invasive aspergillosis

Invasive aspergillosis (IA) is a severe infection that can occur in severely immunocompromised patients. Efficient immune recognition of Aspergillus is crucial to protect against infection, and previous studies suggested a role for NOD2 in this process. However, thorough investigation of the impact...

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Detalles Bibliográficos
Autores principales: Gresnigt, Mark S., Cunha, Cristina, Jaeger, Martin, Gonçalves, Samuel M., Malireddi, R. K. Subbarao, Ammerdorffer, Anne, Lubbers, Rosalie, Oosting, Marije, Rasid, Orhan, Jouvion, Grégory, Fitting, Catherine, Jong, Dirk J. de, Lacerda, João F., Campos, António, Melchers, Willem J. G., Lagrou, Katrien, Maertens, Johan, Kanneganti, Thirumala-Devi, Carvalho, Agostinho, Ibrahim-Granet, Oumaima, van de Veerdonk, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035256/
https://www.ncbi.nlm.nih.gov/pubmed/29980664
http://dx.doi.org/10.1038/s41467-018-04912-3