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miR-103 promotes endothelial maladaptation by targeting lncWDR59

Blood flow at arterial bifurcations and curvatures is naturally disturbed. Endothelial cells (ECs) fail to adapt to disturbed flow, which transcriptionally direct ECs toward a maladapted phenotype, characterized by chronic regeneration of injured ECs. MicroRNAs (miRNAs) can regulate EC maladaptation...

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Detalles Bibliográficos
Autores principales: Natarelli, Lucia, Geißler, Claudia, Csaba, Gergely, Wei, Yuanyuan, Zhu, Mengyu, di Francesco, Andrea, Hartmann, Petra, Zimmer, Ralf, Schober, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035258/
https://www.ncbi.nlm.nih.gov/pubmed/29980665
http://dx.doi.org/10.1038/s41467-018-05065-z