G1P3 (IFI6), a mitochondrial localised antiapoptotic protein, promotes metastatic potential of breast cancer cells through mtROS

BACKGROUND: Redox deregulations are ubiquitous in cancer cells. However, the role of mitochondrial redox deregulation in metastasis remains unclear. In breast cancer, upregulation of mitochondrial antiapoptotic protein G1P3 (IFI6) was associated with poor distance metastasis-free survival (DMFS). Th...

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Detalles Bibliográficos
Autores principales: Cheriyath, Venugopalan, Kaur, Jaspreet, Davenport, Anne, Khalel, Ashjan, Chowdhury, Nobel, Gaddipati, Lalitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035266/
https://www.ncbi.nlm.nih.gov/pubmed/29899394
http://dx.doi.org/10.1038/s41416-018-0137-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035266/
https://www.ncbi.nlm.nih.gov/pubmed/29899394
http://dx.doi.org/10.1038/s41416-018-0137-3

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