Cargando…
Inhibition of cytochrome P450 enzymes by thymoquinone in human liver microsomes
The aim of the present study was to investigate the potential effect of thymoquinone (TQ) on the metabolic activity of four major drug metabolizing enzymes in human liver microsomes, namely cytochrome P450 (CYP) 1A2, CYP2C9, CYP2D6 and CYP3A4. The inhibition of CYP enzymatic activities by TQ was eva...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035319/ https://www.ncbi.nlm.nih.gov/pubmed/29989011 http://dx.doi.org/10.1016/j.jsps.2018.02.024 |