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Inhibition of cytochrome P450 enzymes by thymoquinone in human liver microsomes

The aim of the present study was to investigate the potential effect of thymoquinone (TQ) on the metabolic activity of four major drug metabolizing enzymes in human liver microsomes, namely cytochrome P450 (CYP) 1A2, CYP2C9, CYP2D6 and CYP3A4. The inhibition of CYP enzymatic activities by TQ was eva...

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Detalles Bibliográficos
Autores principales:	Albassam, Ahmed A., Ahad, Abdul, Alsultan, Abdullah, Al-Jenoobi, Fahad I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035319/ https://www.ncbi.nlm.nih.gov/pubmed/29989011 http://dx.doi.org/10.1016/j.jsps.2018.02.024

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