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8-Cyclopentyl-1,3-dimethylxanthine enhances effectiveness of antidepressant in behavioral tests and modulates redox balance in the cerebral cortex of mice

The objective of our study was to investigate whether 8-cyclopentyl-1,3-dimethylxanthine (CPT), associated with the adenosine system, enhances the antidepressant efficacy of antidepressant. All experiments were carried out on Albino Swiss mice. Following drugs: CPT (3 mg/kg) and imipramine (15 mg/kg...

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Detalles Bibliográficos
Autores principales: Herbet, Mariola, Szopa, Aleksandra, Serefko, Anna, Wośko, Sylwia, Gawrońska-Grzywacz, Monika, Izdebska, Magdalena, Piątkowska-Chmiel, Iwona, Betiuk, Paulina, Poleszak, Ewa, Dudka, Jarosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035324/
https://www.ncbi.nlm.nih.gov/pubmed/29991913
http://dx.doi.org/10.1016/j.jsps.2018.02.021