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Yokukansan (Kampo medicinal formula) prevents the development of morphine tolerance by inhibiting the secretion of orexin A

BACKGROUND: Yokukansan (YKS), a traditional herbal (Kampo) medicine consisting of seven herbs, is effective in the treatment of pain disorders, such as headache, postherpetic neuralgia, fibromyalgia, and trigeminal neuralgia, and we have previously shown it to be effective against morphine analgesic...

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Detalles Bibliográficos
Autores principales: Katayama, Ayami, Kanada, Yasuaki, Tsukada, Mana, Akanuma, Yuko, Takemura, Haruka, Ono, Takahiro, Suga, Hiroki, Mera, Hitoshi, Hisamitsu, Tadashi, Sunagawa, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035380/
https://www.ncbi.nlm.nih.gov/pubmed/29989049
http://dx.doi.org/10.1016/j.imr.2018.02.005