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Yokukansan (Kampo medicinal formula) prevents the development of morphine tolerance by inhibiting the secretion of orexin A
BACKGROUND: Yokukansan (YKS), a traditional herbal (Kampo) medicine consisting of seven herbs, is effective in the treatment of pain disorders, such as headache, postherpetic neuralgia, fibromyalgia, and trigeminal neuralgia, and we have previously shown it to be effective against morphine analgesic...
Autores principales: | Katayama, Ayami, Kanada, Yasuaki, Tsukada, Mana, Akanuma, Yuko, Takemura, Haruka, Ono, Takahiro, Suga, Hiroki, Mera, Hitoshi, Hisamitsu, Tadashi, Sunagawa, Masataka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035380/ https://www.ncbi.nlm.nih.gov/pubmed/29989049 http://dx.doi.org/10.1016/j.imr.2018.02.005 |
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