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Unlocking pandemic potential: prevalence and spatial patterns of key substitutions in avian influenza H5N1 in Egyptian isolates

BACKGROUND: Avian influenza H5N1 has a high human case fatality rate, but is not yet well-adapted to human hosts. Amino acid substitutions currently circulating in avian populations may enhance viral fitness in, and thus viral adaptation to, human hosts. Substitutions which could increase the risk o...

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Detalles Bibliográficos
Autores principales: Young, Sean G., Kitchen, Andrew, Kayali, Ghazi, Carrel, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035396/
https://www.ncbi.nlm.nih.gov/pubmed/29980172
http://dx.doi.org/10.1186/s12879-018-3222-6