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Rational modification of tricarboxylic acid cycle for improving l-lysine production in Corynebacterium glutamicum
BACKGROUND: Oxaloacetate (OAA) and l-glutamate are essential precursors for the biosynthesis of l-lysine. Reasonable control of all potentially rate-limiting steps, including the precursors supply rate, is of vital importance to maximize the efficiency of l-lysine fermentation process. RESULTS: In t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035423/ https://www.ncbi.nlm.nih.gov/pubmed/29981572 http://dx.doi.org/10.1186/s12934-018-0958-z |