Rational modification of tricarboxylic acid cycle for improving l-lysine production in Corynebacterium glutamicum

BACKGROUND: Oxaloacetate (OAA) and l-glutamate are essential precursors for the biosynthesis of l-lysine. Reasonable control of all potentially rate-limiting steps, including the precursors supply rate, is of vital importance to maximize the efficiency of l-lysine fermentation process. RESULTS: In t...

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Detalles Bibliográficos
Autores principales: Xu, Jian-Zhong, Wu, Ze-Hua, Gao, Shi-Jun, Zhang, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035423/
https://www.ncbi.nlm.nih.gov/pubmed/29981572
http://dx.doi.org/10.1186/s12934-018-0958-z

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