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Haemolysis and haem oxygenase-1 induction during persistent “asymptomatic” malaria infection in Burkinabé children

BACKGROUND: The haemolysis associated with clinical episodes of malaria results in the liberation of haem, which activates the enzyme haem oxygenase-1 (HO-1). HO-1 has been shown to reduce neutrophil function and increase susceptibility to invasive bacterial disease. However, the majority of communi...

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Detalles Bibliográficos
Autores principales: Mooney, Jason P., Barry, Aissata, Gonçalves, Bronner P., Tiono, Alfred B., Awandu, Shehu S., Grignard, Lynn, Drakeley, Chris J., Bottomley, Christian, Bousema, Teun, Riley, Eleanor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035425/
https://www.ncbi.nlm.nih.gov/pubmed/29980206
http://dx.doi.org/10.1186/s12936-018-2402-6