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Haemolysis and haem oxygenase-1 induction during persistent “asymptomatic” malaria infection in Burkinabé children
BACKGROUND: The haemolysis associated with clinical episodes of malaria results in the liberation of haem, which activates the enzyme haem oxygenase-1 (HO-1). HO-1 has been shown to reduce neutrophil function and increase susceptibility to invasive bacterial disease. However, the majority of communi...
Autores principales: | Mooney, Jason P., Barry, Aissata, Gonçalves, Bronner P., Tiono, Alfred B., Awandu, Shehu S., Grignard, Lynn, Drakeley, Chris J., Bottomley, Christian, Bousema, Teun, Riley, Eleanor M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035425/ https://www.ncbi.nlm.nih.gov/pubmed/29980206 http://dx.doi.org/10.1186/s12936-018-2402-6 |
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