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Modeling protein folding in vivo
ABSTRACT: A half century of studying protein folding in vitro and modeling it in silico has not provided us with a reliable computational method to predict the native conformations of proteins de novo, let alone identify the intermediates on their folding pathways. In this Opinion article, we sugges...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035440/ https://www.ncbi.nlm.nih.gov/pubmed/29980221 http://dx.doi.org/10.1186/s13062-018-0217-6 |