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mTOR and ROS regulation by anethole on adipogenic differentiation in human mesenchymal stem cells

BACKGROUND: Adipocyte differentiation of human mesenchymal stem cells (hMSCs) is dependent on mitochondrial metabolism and reactive oxygen species (ROS) to initiate adipocyte differentiation. Although anethole has been known as an anti-oxidant and lipid peroxidation inhibitor, there is little invest...

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Detalles Bibliográficos
Autores principales: Rhee, Yun-Hee, Moon, Jeong Hwan, Mo, Ji-Hun, Pham, Tiffany, Chung, Phil-Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035441/
https://www.ncbi.nlm.nih.gov/pubmed/29980168
http://dx.doi.org/10.1186/s12860-018-0163-2