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Differentiation Therapy by Epigenetic Reconditioning Exerts Antitumor Effects on Liver Cancer Cells

Primary liver tumors are mainly represented by hepatocellular carcinoma (HCC), one of the most aggressive and resistant forms of cancer. Liver tumorigenesis is characterized by an accumulation of epigenetic abnormalities, leading to gene extinction and loss of hepatocyte differentiation. The aim of...

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Detalles Bibliográficos
Autores principales: Gailhouste, Luc, Liew, Lee Chuen, Yasukawa, Ken, Hatada, Izuho, Tanaka, Yasuhito, Nakagama, Hitoshi, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035736/
https://www.ncbi.nlm.nih.gov/pubmed/29759938
http://dx.doi.org/10.1016/j.ymthe.2018.04.018