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Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering
Elucidating the rules for receptor triggering in cell-cell and cell-matrix contacts requires precise control of ligand positioning in three dimensions. Here, we use the T cell receptor (TCR) as a model and subject T cells to different geometric arrangements of ligands, using a nanofabricated single-...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035778/ https://www.ncbi.nlm.nih.gov/pubmed/29713075 http://dx.doi.org/10.1038/s41565-018-0113-3 |