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L1 retrotransposition in the soma: a field jumping ahead

Retrotransposons are transposable elements (TEs) capable of “jumping” in germ, embryonic and tumor cells and, as is now clearly established, in the neuronal lineage. Mosaic TE insertions form part of a broader landscape of somatic genome variation and hold significant potential to generate phenotypi...

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Detalles Bibliográficos
Autores principales: Faulkner, Geoffrey J., Billon, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035798/
https://www.ncbi.nlm.nih.gov/pubmed/30002735
http://dx.doi.org/10.1186/s13100-018-0128-1