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Toxicity and Safety Evaluation of Doxorubicin-Loaded Cockleshell-Derived Calcium Carbonate Nanoparticle in Dogs

Doxorubicin (DOX) is a potent anticancer agent with cytotoxic effects which limit its clinical usage. This effect is due to its nonselective nature causing injury to the cells as a result of reactive free oxygen radical's release. Cockleshell-derived calcium carbonate nanoparticle (CS-CaCO(3)NP...

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Detalles Bibliográficos
Autores principales: Danmaigoro, Abubakar, Selvarajah, Gayathri Thevi, Mohd Noor, Mohd Hezmee, Mahmud, Rozi, Abu Bakar, Md Zuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035816/
https://www.ncbi.nlm.nih.gov/pubmed/30079088
http://dx.doi.org/10.1155/2018/4848602