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Proscillaridin A induces apoptosis, inhibits STAT3 activation and augments doxorubicin toxicity in prostate cancer cells

Cardiac glycosides are natural compounds used for the treatment of congestive heart failure and cardiac arrhythmias. Recently, they have been reported to exhibit anticancer activity. Proscillaridin A (PSN-A), a cardiac glycoside constituent of Urginea maritima has been shown to exhibit anticancer ac...

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Detalles Bibliográficos
Autores principales: He, Yangyang, Khan, Muhammad, Yang, Jingbo, Yao, Min, Yu, Shili, Gao, Hongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036078/
https://www.ncbi.nlm.nih.gov/pubmed/30008594
http://dx.doi.org/10.7150/ijms.23270