In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1

The G protein-coupled bile acid receptor (GPBAR1) has been recognized as a promising new target for the treatment of diverse diseases, including obesity, type 2 diabetes, fatty liver disease and atherosclerosis. The identification of novel and potent GPBAR1 agonists is highly relevant, as these dise...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirchweger, Benjamin, Kratz, Jadel M., Ladurner, Angela, Grienke, Ulrike, Langer, Thierry, Dirsch, Verena M., Rollinger, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036132/
https://www.ncbi.nlm.nih.gov/pubmed/30013964
http://dx.doi.org/10.3389/fchem.2018.00242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036132/
https://www.ncbi.nlm.nih.gov/pubmed/30013964
http://dx.doi.org/10.3389/fchem.2018.00242

Ejemplares similares