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DNA Damage Repair and Drug Efflux as Potential Targets for Reversing Low or Intermediate Ciprofloxacin Resistance in E. coli K-12

Ciprofloxacin is a potent antibacterial drug that is widely used in human clinical applications. As a consequence of its extensive use, resistance has emerged in almost all clinically relevant bacterial species. A mean to combat the observed ciprofloxacin resistance is by reversing it via co-adminis...

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Detalles Bibliográficos
Autores principales: Klitgaard, Rasmus N., Jana, Bimal, Guardabassi, Luca, Nielsen, Karen L., Løbner-Olesen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036142/
https://www.ncbi.nlm.nih.gov/pubmed/30013537
http://dx.doi.org/10.3389/fmicb.2018.01438