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Trehalose inhibits H(2)O(2)-induced autophagic death in dopaminergic SH-SY5Y cells via mitigation of ROS-dependent endoplasmic reticulum stress and AMPK activation
Autophagy is a catabolic process to maintain intracellular homeostasis via removal of cytoplasmic macromolecules and damaged cellular organelles through lysosome-mediated degradation. Trehalose is often regarded as an autophagy inducer, but we reported previously that it could prevent ischemic insul...
Autores principales: | Gao, Zhijie, Wang, Helei, Zhang, Bo, Wu, Xuemei, Zhang, Yanfeng, Ge, Pengfei, Chi, Guangfan, Liang, Jianmin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036158/ https://www.ncbi.nlm.nih.gov/pubmed/30013443 http://dx.doi.org/10.7150/ijms.25656 |
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