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Screening Mammalian Cochlear Hair Cells to Identify Critical Processes in Aminoglycoside-Mediated Damage

There is considerable interest in discovering drugs with the potential to protect inner ear hair cells (HCs) from damage. One means of discovery is to screen compound libraries. Excellent screening protocols have been developed employing cell lines derived from the cochlea and zebrafish larvae. Howe...

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Detalles Bibliográficos
Autores principales: Lim, Hyun Woo, Pak, Kwang, Ryan, Allen F., Kurabi, Arwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036173/
https://www.ncbi.nlm.nih.gov/pubmed/30013464
http://dx.doi.org/10.3389/fncel.2018.00179