Unprecedented in Vitro Antitubercular Activitiy of Manganese(II) Complexes Containing 1,10-Phenanthroline and Dicarboxylate Ligands: Increased Activity, Superior Selectivity, and Lower Toxicity in Comparison to Their Copper(II) Analogs

Mycobacterium tuberculosis is the etiologic agent of tuberculosis. The demand for new chemotherapeutics with unique mechanisms of action to treat (multi)resistant strains is an urgent need. The objective of this work was to test the effect of manganese(II) and copper(II) phenanthroline/dicarboxylate...

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Detalles Bibliográficos
Autores principales: McCarron, Pauraic, McCann, Malachy, Devereux, Michael, Kavanagh, Kevin, Skerry, Ciaran, Karakousis, Petros C., Aor, Ana C., Mello, Thaís P., Santos, André L. S., Campos, Débora L., Pavan, Fernando R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036174/
https://www.ncbi.nlm.nih.gov/pubmed/30013535
http://dx.doi.org/10.3389/fmicb.2018.01432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036174/
https://www.ncbi.nlm.nih.gov/pubmed/30013535
http://dx.doi.org/10.3389/fmicb.2018.01432

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