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Regulation of Leukocytes by TspanC8 Tetraspanins and the “Molecular Scissor” ADAM10

A disintegrin and metalloproteinase 10 (ADAM10) is a ubiquitous transmembrane protein that functions as a “molecular scissor” to cleave the extracellular regions from its transmembrane target proteins. ADAM10 is well characterized as the ligand-dependent activator of Notch proteins, which control ce...

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Detalles Bibliográficos
Autores principales: Matthews, Alexandra L., Koo, Chek Ziu, Szyroka, Justyna, Harrison, Neale, Kanhere, Aditi, Tomlinson, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036176/
https://www.ncbi.nlm.nih.gov/pubmed/30013551
http://dx.doi.org/10.3389/fimmu.2018.01451