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Regulation of Leukocytes by TspanC8 Tetraspanins and the “Molecular Scissor” ADAM10
A disintegrin and metalloproteinase 10 (ADAM10) is a ubiquitous transmembrane protein that functions as a “molecular scissor” to cleave the extracellular regions from its transmembrane target proteins. ADAM10 is well characterized as the ligand-dependent activator of Notch proteins, which control ce...
Autores principales: | Matthews, Alexandra L., Koo, Chek Ziu, Szyroka, Justyna, Harrison, Neale, Kanhere, Aditi, Tomlinson, Michael G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036176/ https://www.ncbi.nlm.nih.gov/pubmed/30013551 http://dx.doi.org/10.3389/fimmu.2018.01451 |
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