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IFN-γ Regulates the Expression of MICA in Human Corneal Epithelium Through miRNA4448 and NFκB

PURPOSE: Major histocompatibility complex class I-related chain A (MICA), a non-classical major histocompatibility complex molecule, can stimulate or co-stimulate CD8+ T cells or natural killer (nk) cells, thus affecting cornea allograft survival. This study investigated IFN-γ regulation of MICA exp...

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Detalles Bibliográficos
Autores principales: Wu, Dan, Zhang, Jing, Qian, Tingting, Dai, Yiqin, Mashaghi, Alireza, Xu, Jianjiang, Hong, Jiaxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036181/
https://www.ncbi.nlm.nih.gov/pubmed/30013574
http://dx.doi.org/10.3389/fimmu.2018.01530