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Granulocyte-Colony Stimulating Factor-Overexpressing Mesenchymal Stem Cells Exhibit Enhanced Immunomodulatory Actions Through the Recruitment of Suppressor Cells in Experimental Chagas Disease Cardiomyopathy

Genetic modification of mesenchymal stem cells (MSCs) is a promising strategy to improve their therapeutic effects. Granulocyte-colony stimulating factor (G-CSF) is a growth factor widely used in the clinical practice with known regenerative and immunomodulatory actions, including the mobilization o...

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Detalles Bibliográficos
Autores principales: Silva, Daniela N., Souza, Bruno S. F., Vasconcelos, Juliana F., Azevedo, Carine M., Valim, Clarissa X. R., Paredes, Bruno D., Rocha, Vinicius P. C., Carvalho, Gisele B., Daltro, Pamela S., Macambira, Simone G., Nonaka, Carolina K. V., Ribeiro-dos-Santos, Ricardo, Soares, Milena B. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036245/
https://www.ncbi.nlm.nih.gov/pubmed/30013550
http://dx.doi.org/10.3389/fimmu.2018.01449