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Granulocyte-Colony Stimulating Factor-Overexpressing Mesenchymal Stem Cells Exhibit Enhanced Immunomodulatory Actions Through the Recruitment of Suppressor Cells in Experimental Chagas Disease Cardiomyopathy
Genetic modification of mesenchymal stem cells (MSCs) is a promising strategy to improve their therapeutic effects. Granulocyte-colony stimulating factor (G-CSF) is a growth factor widely used in the clinical practice with known regenerative and immunomodulatory actions, including the mobilization o...
Autores principales: | Silva, Daniela N., Souza, Bruno S. F., Vasconcelos, Juliana F., Azevedo, Carine M., Valim, Clarissa X. R., Paredes, Bruno D., Rocha, Vinicius P. C., Carvalho, Gisele B., Daltro, Pamela S., Macambira, Simone G., Nonaka, Carolina K. V., Ribeiro-dos-Santos, Ricardo, Soares, Milena B. P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036245/ https://www.ncbi.nlm.nih.gov/pubmed/30013550 http://dx.doi.org/10.3389/fimmu.2018.01449 |
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