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Predicting the Effectiveness of Hepatitis C Virus Neutralizing Antibodies by Bioinformatic Analysis of Conserved Epitope Residues Using Public Sequence Data

Hepatitis C virus (HCV) is a global health issue. Although direct-acting antivirals are available to target HCV, there is currently no vaccine. The diversity of the virus is a major obstacle to HCV vaccine development. One approach toward a vaccine is to utilize a strategy to elicit broadly neutrali...

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Detalles Bibliográficos
Autores principales: Cowton, Vanessa M., Singer, Joshua B., Gifford, Robert J., Patel, Arvind H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036255/
https://www.ncbi.nlm.nih.gov/pubmed/30013555
http://dx.doi.org/10.3389/fimmu.2018.01470