Vγ9Vδ2 T Cells in the Bone Marrow of Myeloma Patients: A Paradigm of Microenvironment-Induced Immune Suppression

Vγ9Vδ2 T cells are non-conventional T cells with a natural inclination to recognize and kill cancer cells. Malignant B cells, including myeloma cells, are privileged targets of Vγ9Vδ2 T cells in vitro. However, this inclination is often lost in vivo due to multiple mechanisms mediated by tumor cells...

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Detalles Bibliográficos
Autores principales: Castella, Barbara, Foglietta, Myriam, Riganti, Chiara, Massaia, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036291/
https://www.ncbi.nlm.nih.gov/pubmed/30013559
http://dx.doi.org/10.3389/fimmu.2018.01492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036291/
https://www.ncbi.nlm.nih.gov/pubmed/30013559
http://dx.doi.org/10.3389/fimmu.2018.01492

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