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Decreased argininosuccinate synthetase expression in Thai patients with cholangiocarcinoma and the effects of ADI-PEG20 treatment in CCA cell lines

Cholangiocarcinoma (CCA) is a severe cancer with poor prognosis. The aim of the present study was to explore the expression of argininosuccinate synthetase (ASS), as well as the possibility of using pegylated arginine deiminase (ADI-PEG20) for the treatment of CCA. ASS expression was determined in C...

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Detalles Bibliográficos
Autores principales: Roeksomtawin, Somphon, Navasumrit, Panida, Waraprasit, Somchamai, Parnlob, Varabhorn, Sricharunrat, Thaniya, Bhudhisawasdi, Vajarabhongsa, Savaraj, Niramol, Ruchirawat, Mathuros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036342/
https://www.ncbi.nlm.nih.gov/pubmed/30008833
http://dx.doi.org/10.3892/ol.2018.8807