How Tumor Cells Choose Between Epithelial-Mesenchymal Transition and Autophagy to Resist Stress—Therapeutic Implications

Tumor cells undergo epithelial-mesenchymal transition (EMT) or macroautophagy (hereafter autophagy) in response to stressors from the microenvironment. EMT ensues when stressors act on tumor cells in the presence of nutrient sufficiency, and mechanistic target of rapamycin (mTOR) appears to be the c...

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Detalles Bibliográficos
Autores principales: Marcucci, Fabrizio, Rumio, Cristiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036460/
https://www.ncbi.nlm.nih.gov/pubmed/30013478
http://dx.doi.org/10.3389/fphar.2018.00714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036460/
https://www.ncbi.nlm.nih.gov/pubmed/30013478
http://dx.doi.org/10.3389/fphar.2018.00714

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