ADME/toxicity prediction and antitumor activity of novel nitrogenous heterocyclic compounds designed by computer targeting of alkylglycerone phosphate synthase

Alkylglycerone phosphate synthase (AGPS) is an oncogene and can be considered as an antitumor drug target. The aim of the present study was to design novel nitrogenous heterocyclic compound improving targetability by computer-aided drug design technology targeting AGPS. A total of 12 nitrogenous het...

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Detalles Bibliográficos
Autores principales: Zhu, Yu, Han, Yuan, Ma, Ying, Yang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036461/
https://www.ncbi.nlm.nih.gov/pubmed/30008821
http://dx.doi.org/10.3892/ol.2018.8873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036461/
https://www.ncbi.nlm.nih.gov/pubmed/30008821
http://dx.doi.org/10.3892/ol.2018.8873

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