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Arginine methyltransferase inhibitor-1 inhibits sarcoma viability in vitro and in vivo

Protein arginine methyltransferases (PRMTs) are a class of epigenetic modified enzymes that are overexpressed in a various types of cancer and serve pivotal functions in malignant transformation. Arginine methyltransferase inhibitor-1 (AMI-1) is a symmetrical sulfonated urea that inhibits the activi...

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Detalles Bibliográficos
Autores principales: Zhang, Baolai, Chen, Xue, Ge, Suyin, Peng, Caili, Zhang, Su, Chen, Xu, Liu, Tao, Zhang, Wenkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036477/
https://www.ncbi.nlm.nih.gov/pubmed/30008914
http://dx.doi.org/10.3892/ol.2018.8929